Avanafil is used to treat erectile dysfunction (ED: impotence; inability to get or maintain an erection in men). Avanafil belongs to a class of drugs called phosphodiesterase (PDE) inhibitors. It works by increasing blood flow to the penis during sexual stimulation. This increased blood flow can cause an erection. Avanafil does not cure erectile dysfunction or increase sexual desire. Avanafil does not prevent pregnancy or the spread of sexually transmitted diseases such as human immunodeficiency virus (HIV). Impotence is one such sexual condition millions of men are suffering with. One need to take necessary precaution and treat this condition at an initial level to make it easy to treat.

Composition

Avanafil is a phosphodiesterase-5 (PDE5) inhibitor used to treat erectile dysfunction. Compared to other drugs of the same class, it shows greater selectivity for PDE5 over PDE6 than both sildenafil and vardenafil, but less selectivity than tadalafil, suggesting a relatively lower risk of visual disturbances associated with off-target inhibition of PDE6. This component is chemically formulated as C23H26ClN7O3 with the known systematic name as (S)-4-((3-chloro-4-methoxybenzyl)amino)-2-(2-(hydroxymethyl)pyrrolidines-1-yl)-N-(pyrimidine-2-ylmethyl)pyrimidine-5-carboxamide and molecular weight as 483.951 g/mol.

Dosages

50 mg – The first dose that goes is 50 mg which is one most suitable for people suffering from initial level of erectile dysfunction. This is the time when he starts suffering from impotence or he is not able to keep his penile erect during his private moment or sexual intercourse.

100 mg – The second dose that goes in the line is 100 mg. This is the stage when you are already suffering from the condition and your condition is not getting cured by the normal and early dose of 50 mg. this condition is little serious and might take time to get treated. It is better to get treated before things get worse.

200 mg – This is the heaviest dose that comes under avanafil. This medicine is taken when the man is suffering from severe issues of erectile dysfunction or popularly known as impotence. This is the last dosage that comes under avanafil. 200 mg pill of avanafil is perfect for males suffering from severe issues and they are not able to meet it with 50 mg, 100 mg or 200 mg.

No matter what medicine it is, nothing should be taken without doctor’s opinion. Tell them your condition and sexual life and then ask them for exact medication and dosages.

How Does Avanafil Work?

Avanafil goes in the blood streams and relaxes the muscles hence provides free-flowing of the blood which result in complete and hard erection.

Uses Of Avanafil

Helps in attaining hard and perfect erection. Helps in improving personal and partnered sexual life.

How To Take Avanafil?

Avanafil is available as an oral tablet. For men taking the 100 mg or 200 mg doses, Avanafil is usually taken as needed, with or without food, about 15 minutes before sexual activity. For men taking the 50 mg dose, Avanafil is usually taken as needed, with or without food, about 30 minutes before sexual activity. Do not take Avanafil more than once every 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part that you do not understand. To understand. Take Avanafil exactly as directed. Do not take more, less or more often than prescribed by your doctor. Your doctor will likely start you on an average avanafil dose and may increase or decrease your dose depending on how you respond to the drug. Let your doctor know if avanafil is not working well or if you experience any side effects. Ask your pharmacist or doctor for a copy of the manufacturer’s information sheet for the patient.

Warning And Precautions

Before taking Avanafil, tell your doctor and pharmacist if you are allergic to Avanafil, other medications, or any of the ingredients in Avanafil tablets. Ask your pharmacist or see patient information for a list of ingredients. Are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate. Nitrates come in the form of tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are unsure if any of your medicines contain nitrates. Do not take illegal medications that contain nitrates such as amyl nitrate and butyl nitrate while taking Avanafil.

Before taking Avanafil, tell your doctor and pharmacist if you are allergic to Avanafil, other medications, or any of the ingredients in Avanafil tablets. Ask your pharmacist or see patient information for a list of ingredients. Are taking or have recently taken riociguat (Adempas) or nitrates such as isosorbide dinitrate (Dilatrate-SR, Isordil, in BiDil), isosorbide mononitrate (Monoket), and nitroglycerin (Minitran, Nitro-Dur, Nitromist, Nitrostat,

others). Nitrates come in the form of tablets, sublingual (under the tongue) tablets, sprays, patches, pastes, and ointments. Ask your doctor if you are unsure if any of your medicines contain nitrates. Do not take illegal medications that contain nitrates such as amyl nitrate and butyl nitrate while taking Avanafil.

Side Effects

Some side effects can be serious when the medicine is taken without the help or consideration of the doctor. If you experience any of these symptoms, call your doctor immediately or get emergency medical treatment:

• an erection that lasts longer than 4 hours
• sudden loss of vision in one or both eyes (see below for more information)
• sudden hearing loss (see below for more information)
• ringing in the ears
• dizziness
• rash
• itching
• swollen eyelids

Avanafil may cause other side effects. Call your doctor if you have any unusual problems while taking this medication.

Some patients experienced sudden partial or complete vision loss after taking avanafil-like drugs. In some cases, the vision loss was permanent. It is not known if the vision loss was caused by the drug. sudden vision loss while taking avanafil, call your doctor right away.to your doctor. Some patients have experienced sudden hearing loss or sudden hearing loss after taking other avanafil-like drugs. The drug caused hearing loss. If you experience sudden hearing loss, sometimes with ringing in the ears or dizziness, while taking Avanafil, contact your doctor immediately. Do not take additional doses of avanafil or similar medications such as sildenafil (Revatio, Viagra), tadalafil (Cialis), or vardenafil (Levitra) until you have spoken to your doctor.

Storage

Keep this medication in its original packaging, tightly closed and out of the reach of children. Store at room temperature and away from excessive heat and humidity (not in the bathroom). Medicines you don’t need should be disposed of in a special way to ensure that pets, children and other people cannot ingest them. However, you should not flush this medicine down the toilet. Instead, the best way to dispose of your medicine is through a medicine take-back program. Talk to your pharmacist or contact your local waste/recycling department to find out about take-back programs in your community. If you do not have access, see the FDA’s Secure Drug It is important to keep all medicines out of the sight and reach of children as many containers (e.g. weekly pill reminders and those for eye drops, creams, patches and inhalers) are not child resistant and may be harmful to minors. Children can easily open them. To protect young children from poisoning, always close safety caps and immediately store medication in a safe place, high up, away and out of sight and reach.

How Should This Medicine Be Used?

Avanafil is available as an oral tablet. For men taking 100 mg or 200 mg doses, Avanafil is usually taken as needed, with or without food, about 15 minutes before sexual activity. For men taking the 50mg dose, Avanafil is usually taken as needed, with or without food, about 30 minutes before sexual activity. Do not take Avanafil more than once every 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part that you do not understand. Take Avanafil exactly as directed. You’ll likely start out with an average avanafil dose and may increase or decrease your dose depending on how you respond to the drug. Let your doctor know if avanafil isn’t working well or you experience any side effects. Ask your pharmacist or doctor for a copy of the manufacturer’s information sheet for the patient.

Other Uses For This Medicine

This medication may be prescribed for other uses; ask your doctor or pharmacist for more information.

Keep all appointments with your doctor. Do not let anyone take your medication. Ask your pharmacist any questions you have about refilling your prescription. It is important that you keep a written list of all prescription and over-the-counter medications you are taking, as well as any products such as vitamins, minerals or other dietary supplements. You should take this list with you whenever you visit a doctor or stay in hospital.  It is also important information to take with you in case of emergencies.

What Special Dietary Requirements Do I Have To Observe?

Talk to your doctor about eating grapefruit and drinking grapefruit juice while taking this medicine.