Cialis is a branded drug, that has acquired approval from the Food and Drug Administration (FDA) for the treatment of erectile dysfunction, also called impotence in men. This drug is composed of Tadalafil, which forms the active ingredient of these drugs. These pills treat impotence problems, by increasing the supply of blood to the male sexual organ. This increased blood flow is due to the vasodilating properties of Cialis. These are available only on prescription, so you have to obtain a prior prescription letter from your healthcare provider to get these pills.
Mechanism of action of Cialis
Cialis drugs are made up of Tadalafil, which is the active ingredient of these pills. It is a phosphodiesterase type 5(PDE5) inhibitor, and its role is to inhibit the PDE5 enzymes from building plaque in the passages of the blood vessels. When the pill is taken, it takes around 30 minutes to metabolize and become completely assimilated within the bloodstream. Its action starts only when the individual who has taken the pill becomes sexually aroused.
Arousal causes the effects of the pill to get activated. The penile blood vessels start releasing more and more nitric oxide in the walls of the penile arteries, which increases the blood circulation in the penile. Further, this relaxation and increased flow of blood revitalizes the erection function and triggers stronger erections.
Cialis Pills
In addition, Cialis pills are branded drugs, which are not affordable to everyone. Only a few can afford these drugs. What makes these drugs so expensive? Cialis drugs lie on the costlier side due to their FDA approval. They are also known for their prolonged action mechanism, which remains for around 36 hours or even more. Also, they get readily assimilated into the bloodstream, which takes around 15 minutes. These are the reasons why these drugs are sold at such costlier prices.
Drugs
For those who cannot shell out a hefty amount on this drug can look for alternative drugs that offer the same benefits as Cialis. Alternatives like Cialis generic will serve as a great remedy for impotence issues. Cialis generic like Tadalista produces similar effects as the branded one. Its effects also last for up to 36 hours and obtain desired results on sexual performance.
Effects of Cialis on blood pressure
The active component of Cialis increases the levels of nitric oxide in the endothelial walls of the penile blood vessels. The chemical, nitric oxide is crucial for the optimal functioning of the penile blood vessels. It manages the constriction of the blood vessels by increasing the relaxation of the strained muscles of the blood vessels.
Vasodilation
Vasodilation and expansion of the blood vessels ease the blood flow through the vascular passages. Without adequate nitric oxide, vasodilation will not happen, and there will be plaque build-up within the passages of the blood vessels. This plaque formation clogs the blood vessels and leads to their hardening. But the Cialis pill increases the nitric oxide levels in the endothelial walls and enables vasodilation.
The constriction and narrowing of the vascular passages increase blood pressure through the blood vessels. This blood pressure can harm the delicate walls of the blood vessels and injure them eventually. Cialis pill opens the narrowed passages of the blood vessels and decreases the blood pressure through the blood vessels. Thus, Cialis reduces blood pressure and restores normal vascular function.
Contraindications of Cialis
The drug works by causing the complete relaxation of blood vessels, which is crucial for easing the blood flow to the penile. It lowers blood pressure, which is necessary for a healthy erectile response. But one needs to be careful while using these drugs. Never take these drugs if you are already using nitrate drugs. If you do not know whether your drug consists of nitrate, then it is necessary to ask your doctor.
Nitrates
Nitrates’ interaction with Cialis pills can lead to a severe drop in blood pressure, which can cause life-threatening side effects. It is necessary to avoid their interaction. If you are using medications for treating some chronic illnesses like heart disease, angina (chest pain), recent heart surgery, cardiovascular disorders, hypertension (high blood pressure), etc., then Cialis pills are not suitable for you. Your doctor might ask you to avoid using Cialis pills in such cases.
Drugs that have nitrate in them include isosorbide drugs, nitroglycerin, diuretics, alpha-blockers, and other vasodilator medications. Their combination can lead to a sudden drop in blood pressure, which can potentiate the risk of organ failure and even death.
Indications of severe blood pressure drop
After using Cialis pills, if you experience a drop in your blood pressure, you might encounter symptoms like fainting, fatigue, depression, blurred vision, lack of concentration, breathing troubles, pale skin, dehydration, or excessive thirst. In case you undergo any of these, stop taking these pills and see your doctor immediately, this will help to prevent fatal effects.
The lowdown
Although Cialis pills cause a slight drop in blood pressure, which is much needed for proper functioning of sexual function. It becomes a problem when the blood pressure drops drastically, leading to symptoms like fainting, dizziness, fatigue, etc. If so happens, then stop taking the pills right away and talk to your healthcare provider. They may inquire about some of your medical history and your current health condition. Based on the analysis, they will suggest a proper remedy for your sexual problem.
